A summation of Biohazard Zero, divided up into three acts where the player chooses between Rebecca Chambers or Billy Coen. The first act follows Rebecca and Billy through the train and ends with a boss battle with the Stinger. The second takes place in the Umbrella Research Center and the church and a boss battle with the Infected Bat. The last scenario takes place in bowels of the Arklay Treatment Plant and the battle with the Queen Leech.
Reveals Wesker's actions during this timeframe. The t-Virus escaped in Umbrella's Training Facility due to Dr. Marcus' attack and Wesker must escape from the facility in order to pursue his next mission, luring the S.T.A.R.S. team to the Arklay Laboratory. The Proto Tyrant (T-001 Model)'s death is retconned as being at the hands of Wesker. After successfully reaching the surface, Sergei Vladimir confronts him and, not noticing Wesker's betrayal and unknowingly mistaking his actions as failure, dispatches a derivation of the Tyrant (T-103 Model)s called Ivan to punish him. Wesker barely manages to escape with his life.
Nightmare 1 & 2
Rebecca Chambers and Richard Aiken meet up at the Spencer Mansion and try to find Enrico Marini. This scenario also shows how Yawn attacked Richard.
A summarization of Biohazard, divided into three acts where the player can choose between Chris Redfield and Jill Valentine. It first follows them through their meeting with the Spencer Mansion ending with a battle with the Yawn and Rebecca's level. Then through the gardens and outer areas, ending with a battle with the Plant 42. And finally through the labs and a battle with the Tyrant (T-002 Model).
Wesker awakes in basement level four of the Arklay Laboratory, resurrected by a special virus sample he received from William Birkin and discovers that the Tyrant has been destroyed and the mansion's self-destruct system has been activated. He attempts to get Umbrella's data but has to realize that it has been backed up to a supercomputer called U.M.F.-013 by Sergei Vladimir. Furthermore, his access privileges to the mainframe system have been revoked by Red Queen. With minutes to spare, Wesker changes his plans and fights his way out of the mansion. At the very end, he finds the exit blocked by his long lasting test subject, the nearly immortal Lisa Trevor, whom he decides to give the final treatment.
A summation of Last Escape, divided up into three levels where the player can choose between Jill Valentine or Carlos Oliveira.
- Part 1: This segment follows Jill and Carlos' way to the Train Station. . The Boss is the Grave Digger.
- Part 2:This segment follows Jill and Carlos going through a train station to the R.P.D., at the end of this segment the player/s must combat over 20 Hunter Rs'.
- Part 3: This final segment follows Jill and Carlos' exploration through the R.P.D., and their fight with the Nemesis.
Covers Ada Wong's mission to bring the G-virus sample back to Wesker. Although heavily injured during the events of Biohazard 2, Ada survived and returned to the surface. She attempts to rendezvous with a contact at the Apple Inn, but finds him already dead due to suicide. Wesker then contacts her via phone and informs her that she has failed, and that her betraying them and rescuing Leon S. Kennedy would have consequences for their organization. Ada shows Wesker a tissue fragment of Birkin's dead body serving as a sample of the G-Virus, at which point he tells her that Raccoon City is about to be bombed and a helicopter with an Umbrella officer is the only possibility to leave the town, thus saving her life through the information. Ada handily defeats a Tyrant R that was absorbed by Nyx. After the fight, she uses the grapple gun she collected from the dead contact to board the chopper. Inside the helicopter, Sergei Vladimir and an unnamed Umbrella executive talk about stealing the computer core, U.M.F.-013, from his own company.
A retelling of the bonus scenario of the same name introduced in Biohazard 2. It covers special agent HUNK's mission to return the G-virus sample to Umbrella. In this remake, radio interference causes the player to pick up a variety of transmissions, such as the police's doomed attempts to fight the zombies, the last broadcast of a surrounded radio station, advertisements for various Umbrella products, the dying pleas of HUNK's only surviving teammate, and someone screaming "Raccoon City! Raccoon City!". HUNK makes it to the roof of the police department and is picked up by a rescue chopper.
A three-part story dealing with Chris Redfield and Jill Valentine attacking and securing Umbrella's most important remaining facility, the Russian stronghold in the Caucasus region where the Red Queen supercomputer and all of Umbrella's data is being held. Anticipating an attack, Sergei Vladimir unleashed the t-Virus in his own facility, along with the most powerful B.O.W.s the company had to offer. Jill and Chris penetrate deep into the facility, ultimately destroying Umbrella's most sophisticated bio-weapon ever, the T-A.L.O.S. project.
Chris and Jill unintentionally cause a diversion, Albert Wesker also infiltrates Sergei's stronghold with a much more insidious mission. Sergei soon confronts Wesker, and sends two of his Tyrants to kill him. Wesker proves to be more than a match for Ivan thanks to his superhuman abilities, and continues his infiltration of the facility. In the end, Wesker faces Sergei for the last time, who self-destructs himself with the t-Virus and mutates him into a monster. Wesker kills him and steals all the data Umbrella accumulated over years of research, and then wipes the computer clean. By gaining the data, Wesker starts his plan to revive the Umbrella Corporation under his command, as revealed in Biohazard 4 to be his main objective.